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On the advice of the Committee on the Safety of Medicines (now the Commission on Human Medicines), benzodiazepines are indicated for the short-term relief of anxiety that is severe, disabling or subjecting the individual to unacceptable distress, occurring alone or in association with insomnia or short-term psychosomatic, organic or psychotic illness. Benzodiazepines should be used for as short a term as possible (two to four weeks is recommended) because both physical and psychological dependence develop to these drugs and withdrawal can be difficult after only a few weeks.

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