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Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. These medicines may interact and cause very harmful effects.
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- It has a slow onset of action, up to eight hours when used for nerve block.
- Sodium ion channels can be in three different states open, closed or inactivated.
- See Figure Phase reactions to a more water-soluble metabolite, which is more likely to be excreted by the kidney or go on to Phase reaction, which involves the addition of oxygen to the drug molecule.
- Collectively cardiac muscle is known as the myocardium.
Corticosteroids used for inhalation are generally poorly absorbed into the circulation thereby reducing the possibility of systemic side effects. Oral corticosteroids are sometimes needed in short courses to manage acute exacerbation and longer term when other drugs do not prevent severe attacks of asthma.
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Tyramine and indirectly-acting sympathomimetic drugs are normally broken down by monoamine oxidase in the tissues. If the enzyme is inhibited these substances cause rapid elevation in blood pressure leading to a hypertensive crisis, which can be fatal.
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Any GSL, P or POM medicine (including controlled drugs since July where there is a patient need and the doctor has agreed in a patients CMP) can be prescribed under a CMP. This includes the prescribing of: (Black triangle drugs are those recently licensed and still being monitored for adverse reactions; unlicensed medicines are those not licensed in the United Kingdom.
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This distinction is often not important clinically. If bacteria are prevented from multiplying, they will eventually be destroyed by the normal immune reaction of the host.
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