Fatal overdose may occur when benzodiazepines are combined with other depressants such as opiates, barbiturates, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances. And I constantly wonder what exactly happened.

Our goal is 1, Feb 12, DOSE: 2. I felt I just had to contribute. My experience with Lorazepam has been a love affair of about 3 years. Nothing bad has happened so far.

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Our goal is 1, Nov 28, DOSE: 7. I have tried many other drugs, including other pharmacy drugs, but never and anti anxiety drug. He had taken 3 of the 1mg pills the night before and said all it did was make him relaxed. So I figured what the hell? I got 7 of the pills from him and went to the bathroom. I downed all 7 pills at once and headed to class. About 5 minutes later I decided to stand up and see if I could feel any effects. I got up and walked across the classroom to throw away a piece of paper, as I walked I noticed that the floor seemed far away and I felt as if I had to step down to reach it.

Get the Erowid Words T-shirt. Feb 28, I am a home-body, and get anxiety any time I have to leave the house for class, work, or just to hang out with friends, so I knew I would need something to help with the anxiety while I was away. I take 1 mg and dissolve it under my tongue before we start the 12 hour drive. As we walk through the casino to our hotel room, I realize I've never tried gambling, and since I'm of age, I might as well take this opportunity to waste a few bucks in the slot machines while I have one drink. I dropped my stuff off in our room, tell my family I'll be back, and head to the casino.

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Jul 26, The dose was 1mg to be taken twice daily. Naturally, knowing the recreational potential of this medication from the getgo, I took 2mg my first night. I just remember laying down on my bed at around 10pm fully clothed which I normally undress before bed and the next minute I'm waking up at noon the next day in exactly the same position I laid down in. I mostly stuck with my doctor's orders of taking the 1mg of Ativan twice daily, with the occasional 5 or 6mg dosages to get trashed. Eventually after a few months it quit working so I asked him to up the dosage to 2mg twice daily.

Erowid relies on the generosity of the public for funding. Feb 10, I was sober for about a month and feeling great. Long story short I decided to drink one night with a couple of close friends and my girlfriend at the time. We started off slow, but slowly picked up. We were taking shots left and right, toasting to everything.

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They have similar physiological effects, which augment activation of the sympathetic nervous system. The adrenal cortex is made up of three distinct layers, each of which secretes a different type of steroid hormone. The outermost layer of the cortex produces aldosterone. Aldosterone is released in response to fall in blood volume andor blood pressure and it increases the rate of sodium and water reabsorption by the kidney distal tubules. This increases blood volume and restores blood pressure. The middle and thickest layer of the cortex produces glucocorticosteroids, the main one being cortisol.

Nifedipine also has a use in the treatment of Raynauds disease. In Raynauds disease, there is inappropriate vasoconstriction in the fingers and toes, usually in response to cold. The condition can be mild or severe leading to ulceration and possibly gangrene of the digits. Raynauds disease can occur on its own, or as a consequence of systemic sclerosis or systemic lupus erythematosus, both chronic inflammatory diseases. Adverse effects of class II calcium channel blockers are reflex tachycardia, headache, flushing, pro lorazepam 2mg and ankle oedema. Class III calcium channel blockers are intermediate in action affecting calcium ion channels in both cardiac muscle cells and smooth muscle cells in blood vessels.

A commonly used example of this type of diuretic is bendroflumethiazide. Loop diuretics inhibit sodium and chloride ion transport in the ascending limb of the loop of Henl´e and therefore prevent water reabsorption there. An example of a loop diuretic is furosemide. Both thiazides and loop diuretics also produce vasodilation, which reduces peripheral vascular resistance and helps reduce blood pressure. Thiazide diuretics are recommended as an alternative to calcium channel blockers as first choice drugs in hypertensive patients over the age of Adverse effects of diuretics are excessive potassium and hydrogen ion loss leading to hypokalaemia and metabolic alkalosis. Hypokalaemia enhances the toxic effects of cardiac glycosides.

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