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Cardiac glycosides interact with many other drugs; some increase the risk of toxicity (for example amiodarone and verapamil) and others reduce it (for example cholestyramine, colestipol and antacids), but also reduce therapeutic effect. Diuretics are used to treat cardiac failure and hypertension. Because cardiac failure results in hypertension and leads to oedema, diuretics are used in both cases because they encourage water loss and therefore produce a reduction in circulating blood volume. This lowers blood pressure, reduces the work the heart has to do and improves oedema by encouraging the movement of fluid from the tissues into the circulation. Of the different types of diuretics, the ones used in cardiac failure and hypertension are thiazide diuretics and loop diuretics.
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Drug therapy aims to prevent cell division or cause cell death in the tumour without damaging normal healthy cells. Cancer cells are similar to normal cells, so this is often impossible and explains many of the side effects of chemotherapy.
- Side effects of riluzole are nausea, vomiting, tachycardia, headache, dizziness and vertigo.
- CMPs should be kept as simple as possible.
- Radiographer-led discharge in accident and emergency the results of a pilot project.
- Flucloxacillin is not affected by penicillinase and is used for staphylococcus infection.
- The drug then diffuses into nervous tissue.
- Anti-inflammatory corticosteroids, for example prednisolone, can be used to suppress the antibody formation in myasthenia gravis.
- There are many drugs in this group of anti-cancer drugs.
An example of a mucolytic is carbocisteine. Mucolytics should be used with caution in patients with a history of peptic ulcer because they may reduce the amount of mucus in the stomach.
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Rarely, the disease is rapidly progressing with joint destruction. The serum is rheumatoid factor negative. Most rheumatic diseases require symptomatic treatment to relieve pain and increase joint movement using non-steroidal anti-inflammatory drugs and anti-inflammatory corticosteroids to limit or stop the inflammation. In addition treatment aims to prevent destruction of joints by the use of disease-modifying antirheumatic drugs. Indeed, use of DMARDs early on in the disease process is now recommended. The British Society for Rheumatology produces clinical guidelines for treatment of rheumatic diseases.
Amorolfine is a novel topical antifungal drug. It has a similar action to terbinafine affecting synthesis of fungal cell membrane ergosterol and is generally fungicidal. Amorolfine is available as a lacquer). The cream is indicated to treat all fungal infections of the skin and the lacquer is indicated for the treatment of onychomycoses. Both preparations are classified as prescription-only medicines but are included in the list of drugs that registered Podiatrists can access and supply. Amorolfine readily enters the stratum corneum and the nail plate but systemic absorption is minimal from topical administration.
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The pituitary gland plays a very important role in the overall control of the endocrine system.
18.04.2017
Ignaz
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I am grateful to Alison Barlow and Peter Bowden for their helpful ideas with matters relating to podiatry and Louise Stuart, MBE for an insight into supplementary prescribing; to Jan Dodgeon for help with topics relevant to radiography and Chris Frames and Chris ONeal for their help with devising physiotherapy case studies. Special thanks are due to those who contributed to Chapter Peter Hogg and his co-authors, and Anthony Waddington (Podiatric Surgeon).
25.05.2016
Anna
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Marlene
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