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Pagets disease is a disorder of bone turnover of unknown aetiology producing characteristic bone deformities. The disease is rarely seen before the age of approximately that is often without symptoms and progresses slowly over many years, being discovered during other investigations in approximately one-fifth of those diagnosed.
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Persistent mood instability with mild episodes Adapted from American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, patient has an exaggerated sense of well-being and enthusiasm and talks non-stop. These signs may be combined with irritability, impatience and anger. Lack of judgement leads to a manic person becoming, for example overgenerous and reckless. They may have grandiose delusions. Hypomania is a milder form of mania and may not require drug therapy.
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Knowledge of family history can help predict who will suffer from adverse reactions.
05.01.2016
Jakob
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It is used as an adjunct to therapy with statins in patients with severe hyperlipidaemia, or alone if statins are not tolerated. Adverse reactions to ezitimibe are gastrointestinal disturbances, headache, fatigue and myalgia.
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They are used as a creams, lotions, ointments and bath oils in concentrations from Coal tar preparations are less irritating to normal skin than dithranol, but can cause folliculitis.
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In high dose, injection of metoclopramide can cause sedation and facial muscle spasms due to effects on dopamine receptors in the brain.
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Supplementary prescribing can be suitable in some areas of community physiotherapy.
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