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These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Drug Exclusivity Exclusivity is the sole marketing buys cytotec generic granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Exclusivity periods can run from days to seven years depending upon the circumstance of the exclusivity grant.
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The mode of action of these two drugs is not fully understood. Chloroquine inhibits digestion of haemoglobin by the parasite and both drugs inhibit the disposal of haem, which is toxic to the parasite.
- Cyclophosphamide produces severe nausea and is often used with a ondansetron.
- However, they have been associated with increased risk of thromboembolic disease and serious skin reactions.
- The importance of this is that highly lipid-soluble drugs, for example benzodiazepines, tend to have prolonged duration of action.
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Levodopa is the precursor of dopamine and it does penetrate the brain where it is converted in the neurons to dopamine by decarboxylation. Levodopa is given orally and in order to maximize the amount that actually reaches the brain, it is given in combination with a decarboxylase inhibitor, carbidopa, which does not enter the brain. Because the drug is not converted into dopamine outside of the brain, this greatly increases the effective dose of levodopa and reduces peripheral side effects. This combination seems to be the best treatment for most Parkinsons patients, at least in the early stages. The site of decarboxylation of levodopa in patients with Parkinsons disease is uncertain, but it may be that there is sufficient enzyme in the remaining dopamine nerve terminals or that conversion takes place in other neurons as they also contain decarboxylase enzymes. Release of dopamine replaced in this way must be very abnormal but most patients seem to benefit.
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