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They stimulate insulin release from β-cells in the pancreas. They are conveniently taken just before each main meal and have a rapid onset and short duration of action. They should be used together with metformin if glucose control is not sufficient with metformin alone. Adverse effects are hypoglycaemia and hypersensitivity rashes.
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Their content is set out by law. A patient specific direction is the traditional prescription written by a doctor, dentist or other qualified prescriber for medicines to be supplied or administered to a named patient. The majority of medicines are supplied or administered in this way.
Designed to inhibit GABA-transaminase, vigabatrin is an anticonvulsant that can be effective in patients resistant to other drugs. Adverse effects of vigabatrin include sedation, dizziness and behavioural changes similar to those seen with phenytoin. Vigabatrin may cause irreversible visual field defects, which limits its use. Lamotrigine is similar in action to phenytoin.
Drugs can be used to lower lipid levels, but changes in diet and control or elimination of other risk factors play an important role in the management of hyperlipidaemia. A in addition to dietary and lifestyle advice. If the changes to lifestyle and diet are recommended and followed by drug therapy if necessary. With a case, the aim is to reduce plasma TC levels to below Individuals with the hereditary form of hyperlipidaemia will always require drug therapy, possibly with two different types.
Characteristic bone deformities result in children and bone pain and tenderness in affected adults. Treatment is by vitamin D replacement. Myasthenia gravis is an autoimmune disease where acetylcholine receptors at the neuromuscular junction are progressively destroyed.
Inhalation anaesthetics currently in use are the volatile liquids halothane and more recently isoflurane, desflurane and sevoflurane and nitrous oxide gas. Halothane is a potent general anaesthetic, which is non-explosive and non-irritant and it provides a pleasant smooth induction. Side effects of halothane include hypotension, cardiac arrhythmias and hangover.
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Another example noted in some PGDs is that working practices may not be in line with Summary of Product Characteristics for that medicinal product. For example some PGDs have indicated that the amount of Omnipaque (an X-ray contrast agent) to be administered can exceed that outlined on the product information sheet.
- There is a potential role for independent prescribers in diagnostic radiography, and this is particularly evident in areas of acute medical practice.
- Analysis of the size and shape of the waves can indicate abnormalities of the heart.
- Vigabatrin may cause irreversible visual field defects, which limits its use.
- Depolarization is initiated by an influx of sodium ions into the cardiac muscle cells, followed by an influx of calcium ions.
Toenail infections will typically require reviews of progress. Side effects are, rarely, pruritis or erythema and a burning sensation in the area of treatment.
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There have been some relatively new developments in the treatment of osteoporosis. Selective oestrogen receptor modulators, for example raloxifene mimic the inhibitory effects of oestrogen on osteoclasts.
Authored by Dr. Sanjay Awasthi, MD
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Vitamin B should not be taken together with levodopa and foods high in vitamin B example liver, walnuts and bananas) should be limited during use of levodopa. These act directly on dopamine receptors in the brain and are selective for the D found in the basal nuclei.
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He tells you that he has been taking a loop diuretic for his mild hypertension and wonders if this drug might have any effect on his use of warfarin. What should you tell him.
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