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This is because the drug has to be in a lipid soluble form to diffuse through the myelin sheath and neuronal membrane. Once inside the neuron dissociation is necessary, because it is the ionized form binds to the sodium ion channel.
30.03.2020
Hildegard
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What advice can you give Mrs Dexter about what appears to be neuropathic pain. You may need to refer to Chapter treatment of neuropathic pain in the BNF.
30.04.2020
Arnold
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The granulomas contain bacteria lying dormant but capable of becoming reactivated later in the patients life if they become ill from some other cause or become immunosuppressed. Treatment for tuberculosis is lengthy taking up to two years and requiring combinations of at least three different antibiotics.
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As far as radiography is concerned, this committee can have a direct impact on practice. Of aspects such as efficacy andor cost implications, and could therefore replace one medicine with another.
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