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The large intestine is where water is reabsorbed from the remains of digested food. Here some drug metabolites that have been excreted in bile can be regenerated by the action of bacteria in the large intestine.
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Gabapentin is used in partial epilepsy together with other drugs that have failed to provide control alone. Adverse effects of gabapentin are gastrointestinal disturbances, mild sedation and ataxia.
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Penicillins bind to the cell wall of bacteria and prevent cross-linking of proteoglycan chains that stabilize the cell wall.
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