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It induces differentiation in leukaemic cells. Monoclonal antibodies have been developed recently which cause lysis of B lymphocytes. These drugs are intended to be used in particular types of leukaemia when other forms of treatment have failed to produce a long-lasting remission. The most serious adverse reaction with these drugs is the so-called cytokine release syndrome. This includes fever and chills, nausea and vomiting and allergic reactions such as rashes, itching, angioedema, bronchospasm and difficulty breathing.
An example is propranolol. Second generation β-blockers have greater cardio-selectivity and are less likely to cause bronchoconstriction. Examples are atenolol and bisoprolol. Third generation β-blockers also cause peripheral vasodilation and do not adversely affect plasma lipid profiles. An example is celiprolol. Calcium channel blockers are used to treat ischaemic heart disease, arrhythmia and hypertension.
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Apart from their local anaesthetic action, local anaesthetics have anticholinergic activity. This is due partly to prevention of acetylcholine release and partly to non-depolarizing competitive block of the acetylcholine receptors on the postsynaptic membrane.
06.03.2018
Eva
Verified
Procarbazine inhibits RNA and DNA synthesis and interferes with mitosis. It is a drug that interacts with alcohol and generally increases the effects of central nervous system depressants and can produce hypertension.
31.07.2020
Wolfram
Verified
Adverse effects of metoclopramide include rashes and pruritis.
30.04.2016
Friedrich
Verified
She prescribes from a personal formulary of drugs within her own area of competence. In practice, this means that the majority of her prescribing is for antibiotics and dressings for the treatment of infected diabetic foot ulcers.
13.02.2018
Eleonora
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Intra-articular injections are sometimes used to administer a drug directly into a joint, for example with a corticosteroid in the treatment of arthritis or a contrast agent for imaging. Intraspinal and epidural injections are given under certain circumstances to have a local effect, either as anaesthesia or to treat infection of the central nervous system.
02.02.2016
Rudolf
Verified