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Dopamine pathways normally balance cholinergic pathways in the basal nuclei and many of the symptoms of Parkinsons disease are thought to be due to over activity of cholinergic pathways. Therapy therefore aims to improve dopaminergic transmission or inhibit cholinergic pathways to restore the balance.
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Treatment is usually with a combination of surgery, irradiation and chemotherapy. The aim of chemotherapy is to interfere with cell division in tumour cells without damaging normal healthy cells.
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