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Inhalation anaesthetics are gases or volatile liquids. Nitrous oxide and isoflurane are commonly used. Intravenous anaesthetics are used to induce general anaesthesia, followed by an inhalation anaesthetic for maintenance, and for short surgical procedures. Propofol is commonly used for both induction and maintenance anaesthesia. Premedication is the use of drugs to reduce a patients anxiety and to prevent parasympathetic effects of the anaesthetic. Muscle relaxants and analgesics are used as adjuncts to anaesthesia, respectively to cause muscle relaxation and aid surgery and to reduce patient discomfort post-operatively. Local anaesthetics are also known as local analgesics because they cause the loss of the sensation of pain in a part of the body.
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The principal groups of drugs that are most likely to cause drugdrug interactions are anticoagulants, oral hypoglycaemics, monoamine oxidase inhibitors (for depression), cytotoxics. These may be due to overdose, genetics, idiosyncrasy, insensitivity, intolerance or hypersensitivity. Adverse reactions are observed more frequently in older people due to increased drug use in this sector of the population. A definition of compliance in this context is the extent to which the behaviour of the patient coincides with the clinical prescription. Although miscompliance is an avoidable error, as many as their medicines as intended.
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- Intravenous general anaesthetics at least seem to work by enhancing the effects of GABA or blocking the effects of glutamate.
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- Mr White is and has decided that he must do something about his lifestyle because he is not keen on taking drugs for the rest of his life.
- There is a yellow card scheme to notify the Medicines and Healthcare Products Regulatory Agency or the Commission on Human Medicines (CHM; formerly the Committee on Safety of Medicines) of unexpected adverse reactions.
Therefore, the risk of adverse effects is increased in patients with hepatic or renal disorders. In addition to their action as local anaesthetics, the following actions on other parts of the body are possible.
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It would be impractical to try to remember the names of all drugs available. In practice, health care professionals quickly become familiar with drugs commonly used in their area.
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Haemophilia is a sex-linked recessive inherited disorder of coagulation. There are two types: haemophilia A, or classical haemophilia, is due to lack of Factor VIII and haemophilia B, or Christmas disease, is due to lack of Factor IX.
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Such reactions require initial exposure to the drug to cause sensitization, after which, subsequent exposure to the same drug triggers an immunological reaction. Although drug allergy is unpredictable, it is more likely to occur in individuals with a history of atopic disease, for example asthma.
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