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For example paramedics can administer certain named drugs in emergency situations.

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They are recommended as the drug of first choice for hypertension in white patients below the age of The most common adverse effect is a chronic dry cough; others are taste disturbances and rashes. ACE inhibitors should not be used in pregnancy.

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Change in pH of the tubular filtrate can affect drug ionization. Manipulation of pH to increase the rate of elimination of a drug has a practical use in cases of overdose as shown by the following examples.

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Biguanides do not affect insulin production but they do require some functioning β-cells to work.

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