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From such observations the monoamine theory of depression and mania was formed: Depression is due to an absolute or relative decrease in monoamines, or a decrease in receptor sensitivity, at certain receptor sites in the brain.

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Lieselotte Verified

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Mania occurs less frequently than depression.

28.10.2018
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The receptor molecule then binds to a particular region of DNA and activates certain genes.

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Wilhelm Verified

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