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Interleukin- killer cells. Tretinoin is the acid form of vitamin A. It induces differentiation in leukaemic cells. Monoclonal antibodies have been developed recently which cause lysis of B lymphocytes. These drugs are intended to be used in particular types of leukaemia when other forms of treatment have failed to produce a long-lasting remission. The most serious adverse reaction with these drugs is the so-called cytokine release syndrome.

Chemotherapy also applies to treatment of cancers. Cancer cells are similar to normal cells and most anticancer drugs show little selective toxicity and therefore produce serious adverse effects. Conventionally, micro-organisms include bacteria, viruses and fungi; protozoa and parasitic worms are parasites. However, bacteria, viruses and fungi are also parasitic, in that they live in or on other living organisms. The term parasite can be applied to any organism that causes disease. A basic knowledge of the characteristics of these organisms is needed in order to understand how they differ from human cells and how these differences can be exploited in chemotherapy.

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