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Metoclopramide is a dopamine antagonist that stimulates gastric emptying and small intestine transit and is used to speed up transit time of barium follow-through examinations. Metoclopramide is also an antiemetic, which can be useful in radiological examinations and to counteract the effects of therapeutic radiography.

  • Examples of fungal infections are candidiasis, aspergillosis and cryptococcus.
  • Rigidity, hypokinesia and tremor are all improved.
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  • They have a lower incidence of side effects than aspirin, but are more expensive and probably no more effective.

Bipolar depression appears to be a complex genetic illness, with susceptible genes interacting with environmental factors and adverse life events. Both depression and mania are associated with changes in brain monoamines.

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Its mechanism of action is by interfering with the synthesis of ergosterol in the fungal cell membrane. Terbinafine inhibits the enzyme that converts a substance called squalene to ergosterol.

This is a diverse group of drugs, which fall into three classes. They all block influx of calcium ions during depolarization of muscle cells. Class I calcium channel blockers work preferentially on calcium ion channels in cardiac muscle cells. This results in a delay in electrical conduction in cardiac muscle, reduced contractility and reduction in the heart rate. Because of these effects, class I calcium channel blockers are used to treat ischaemic heart disease and atrial arrhythmia.

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Examples are salbutamol and salmeterol (long-acting for symptom control at night or before exercise). Side effects of β headache, peripheral vasodilation, tachycardia, and hypokalaemia (low potassium levels) after high doses, and hypersensitivity reactions. It is extremely important that patients are bought phentermine online illegal of the dangers of exceeding the stated dose on inhalers; this would increase the incidence of the above side effects. Antimuscarinic drugs are used to relieve, or at least partially reverse, bronchoconstriction that is refractory to β receptors in the bronchioles. This effectively prevents bronchoconstriction in response to parasympathetic stimulation.


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Neurons are differentially sensitive to local anaesthetics. Small diameter neurons are more susceptible than larger diameter neurons and unmyelinated neurons more than myelinated neurons.

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