What is isotretinoin, and how does it work mechanism of action? What are the uses for isotretinoin? What are the side effects of isotretinoin? Patients may develop an increase in blood cholesterol and triglycerides. Rarely, isotretinoin can cause brain swelling pseudotumor cerebri or intracranial hypertension, which produces nausea, vomiting, headache, and changes in vision. These events may be serious and result in life-threatening events or death, hospitalization, or disability.

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Isotretinoin Capsules 40mg. Type Other. Age Group Adult. Condition New. More details. Isotretinoin accutane is a very powerful retinoid drug used for the treatment of severe acne. Its also used for acne present for many years that has not responded completely to antibiotic pills and creams. Accutane is very effective for nearly all types of breakouts. No other acne medicine works as well for severe acne. It was originally prescribed for people with severe acne that did not respond to other treatments, but has gained in popularity in the past years and is prescribed more and more frequently for less severe acne.

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Get Started. Home Sotret 40mg Capsule. Sotret 40mg Capsule. Composition: Isotretinoin It is used to treat severe nodular acne not responding to other treatments.

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Despite advances in acne therapy in recent years, treatment failure is common. The aim of this study was to investigate the efficacy of low daily dose isotretinoin in moderate to severe acne patients. The secondary objective was to measure the rate of relapse 5 years after the completion of therapy. In this retrospective, noncomparative study, patients with moderate to severe scare prone acne. Liver function tests serum glutamic-oxalocetic transaminase, serum glutamate pyruvate transaminase, direct and total bilirubin, and lipid profiles total cholesterol, low-density lipoprotein, high-density lipoprotein, triglyceride were evaluated for all patients, before the initiation of treatment and again after the 2 nd month of treatment. At the end of treatment course,

Isotretinoin may cause severe birth defects; female patients must not take this medicine if they are pregnant or may likely become pregnant during treatment. Pregnancy should be avoided for 6 months after stopping the treatment. There is an extremely high risk that severe birth defects will result if pregnancy occurs while taking isotretinoin in any amount, even for short periods of time. Potentially any foetus exposed during pregnancy can be affected. Presently, there are no accurate means of determining whether an exposed fetus has been affected. Documented external abnormalities include: skull abnormality; ear abnormalities including anotia, micropinna, small or absent external auditory canals ; eye abnormalities including microphthalmia ; facial dysmorphia; cleft palate.

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Isotretinoin belongs to the drug class retinoids. This medication is used to treat severe cystic acne nodular acne. Isotretinoin is preferred medicine for cystic acne if it has not responded to medications like clindamycin, tetracycline or minocycline. Some of the common side effects of Isotretinoin include: dryness of skin with scaling, changes in skin color, erythema, cheilitis, pruritus, epistaxis, dry eyes, visual disturbances and sometimes conjunctivitis, dry sore mouth Hair thinning, photosensitivity, changes in skin pigmentation, Headache and drowsiness mood changes,depression and anxiety. Isotretinoin has tendency to interact with other medications like vitamin A or progesterone.

Despite advances in acne therapy in recent years, treatment failure is common. Arch Dermatol Res.

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