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  • The initial take up of supplementary prescribing has been slow in the three health care professions.
  • Its significance is that other drugs metabolized by the same enzymes are metabolized faster and therefore circulate in a lower concentration than expected for a given dose.
  • In practice, Clinical Governance Leads are likely to be appropriate, but they can only do so as named individuals.
  • If this happens, the contrast agent may provoke seizures.

Since podiatrists, dieticians, occupational therapists, orthoptists, paramedics, physiotherapists, prosthetists and orthotists, radiographers and speech and language therapists comprise the list of professionals able to supply medicinal products under PGDs. A PGD can include a variable dose range, so the health care professional can decide on a suitable dose for individual patients.

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Fungal infections are known as mycoses and can be either superficial infections of the skin and nails or systemic infection of the internal organs, particularly the lungs. Both types of infection have become more common since the broad-spectrum antibiotics and an increase in numbers of immunocompromized individuals because of HIV infection and the use of immunosuppression and cancer chemotherapy.

This is not completely understood, but appears to be related to protein binding capacity of the molecule. Binding of contrast agent to enzymes in particular can inhibit their activity. For example, inhibition of acetylcholinesterase leads to increased parasympathetic effects. Consequences of this are bronchospasm, a fall in heart rate and hypotension. Protein binding is usually due mail order accutane the electrical charge of ions, but can also be due to the hydrophobic parts of the molecule.

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Hypoglycaemia can occur with any of these drugs and is particularly dangerous in the elderly. Gastrointestinal upsets and allergic skin rashes have been reported, as has bone marrow damage, which is rare but nevertheless severe.

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