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Roaccutane capsules contain the active ingredient isotretinoin. Isotretinoin belongs to a group of medicines known as retinoids, which are derivatives of vitamin A. Isotretinoin taken by mouth works by reducing the production of the skin's natural oil sebum. Acne occurs due to an excessive production of sebum from over-active sebaceous glands in the skin. The sebum blocks the sebaceous glands, which prevents the oil from flowing freely out and causes an accumulation of sebum under the skin.
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She says that normal painkillers do not do any good. What advice can you give Mrs Dexter about what appears to be neuropathic pain. You may need to refer to Chapter treatment of neuropathic pain in the BNF. After cardiovascular disease, cancer is the second major cause of death in the developed world, being the cause of about one in five deaths. It is increasingly common over the age of those commonly occurring such as lung cancer, breast cancer and colon cancer as well as much rarer conditions, some of which occur almost exclusively in children (for example retinoblastoma).
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There are several techniques used to administer local anaesthetics, which are briefly described below. The first three are techniques that can be used by podiatrists in the course of their professional practice providing they are registered with the Health Professions Council and hold a certificate of competence in the use and administration of local anaesthetics. Other techniques for local anaesthetic administration are given for the sake of completeness. EMLA (eutectic mixture of local anaesthetics; a combination of two local anaesthetics, lidocaine and prilocaine in a cream) is capable of producing skin thickness analgesia from topical administration. The cream is applied for a period of occlusive dressing. EMLA is indicated prior to venepuncture and whenever pre-injection analgesia of the skin is required.
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