Zovirax 500mg

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Once diluted for administration, each dose should be used within 24 hours. Each 20 mL vial contains acyclovir sodium equivalent to mg of acyclovir. The resulting solution contains 50 mg acyclovir per mL pH approximately In clinical studies, the average 70 kg adult received between 60 and mL of fluid per dose. Dosage Adjustments for Patients with Renal Impairment Hemodialysis For patients who require dialysis, the mean plasma half-life of acyclovir during hemodialysis is approximately 5 hours. Peritoneal Dialysis No supplemental dose appears to be necessary after adjustment of the dosing interval.

Acyclovir sodium for injection is a sterile lyophilized powder for intravenous administration only. Each mg vial contains mg of acyclovir and 49 mg of sodium, and each 1,mg vial contains 1, mg acyclovir and 98 mg of sodium. The pH of the reconstituted solution is approximately The pka's of acyclovir are 2. This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue.

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Acyclovir is used to treat infections caused by certain types of viruses. It treats cold sores around the mouth caused by herpes simplex, shingles caused by herpes zoster, and chickenpox. This medication is also used to treat outbreaks of genital herpes. In people with frequent outbreaks, acyclovir is used to help reduce the number of future episodes. Acyclovir is an antiviral drug. However, it is not a cure for these infections. The viruses that cause these infections continue to live in the body even between outbreaks. Acyclovir decreases the severity and length of these outbreaks.

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Synthetic antiviral with activity against herpes simplex virus type 1 and 2 and varicella-zoster virus Used to treat herpes labialis, herpes genitalis, herpes simplex encephalitis, herpes simplex keratitis, neonatal herpes infection, chickenpox varicella, shingles zoster. For infants with HSV infection but who have not progressed to HSV disease, treat for 10 days to prevent progression from infection to disease preemptive therapy. For localized disease, treat for 14 days. For CNS or disseminated disease, treat for at least 21 days. If positive, continue IV acyclovir for 7 additional days.

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Physicochemical properties: Acyclovir is a white, crystalline powder with a maximum solubility in water of 1. Those most likely to benefit are patients who experience severe, prolonged recurrences; such intermittent therapy may be more appropriate than suppressive therapy when these recurrences are infrequent. Treatment of Initial Infection of Herpes Genitalis: mg one mg tablet or one teaspoonful of suspension 5 mL every 4 hours, 5 times daily for a total of 1 g daily for 10 days. The initial recommended dose is mg one mg tablet or one teaspoonful of suspension 5 mL three times daily. This can be increased if breakthrough occurs up to a dosage of one mg tablet or one teaspoonful 5 mL of suspension, five times daily.

Zovirax 500mg


This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Zovirax I. Posology and method of administration Route of zovirax 500mg Slow intravenous infusion over 1 hour. A course of treatment with Zovirax I. Treatment for herpes encephalitis usually lasts 10 days.

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The standard course of antiviral therapy for recurrent genital herpes requires administration of multiple doses of medication for 5 days. To assess the efficacy of a shorter course of antiviral therapy, patients with recurrent genital herpes simplex virus type 2 HSV-2 infection were enrolled in a randomized, double-blind, placebo-controlled study of acyclovir mg given by mouth 3 times per day t. Acyclovir therapy mg given by mouth t. A 2-day course of acyclovir is a convenient alternative for treatment of recurrent genital herpes. Antiviral therapy for recurrent genital herpes decreases the duration of lesions, discomfort, and viral shedding 1. To date, such regimens require multiple daily doses administered for 5 days.

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Propofol is the most recently developed intravenous anaesthetic. The site of action of propofol is probably the GABA receptor.

  • Bulk-forming laxatives are long chain polysaccharides, which are not broken down by the normal process of digestion.
  • Topical corticosteroids are effective in most cases of persistent eczema.
  • Be used.
  • The administration of radiopharmaceuticals remains the same as that outlined earlier and as illustrated in the It is anticipated that technicians will soon become HPC registered and shortly after that they are likely to lobby for a range of professional responsibilities, including the use of PGDs.
  • There are in fact five ways in which suitably qualified and registered health care professionals can supply medicines to patients: patient group directions, patient specific directions (PSDs), supplementary prescribing, independent prescribing and specific exemptions to the Medicines Act.
  • However, there is a high risk of teratogenesis and women must use adequate contraception and stop treatment for two years before conception.
  • Adverse reactions can occur with any drug use and can be either related to or unrelated to the expected pharmacological effect.

However, this is not the complete explanation as, for example phenobarbital is far more effective as an anticonvulsant than other barbiturates with the same enhancing effects on GABA. Newer drugs have been shown to interfere with GABA in other ways: by inhibiting GABA-transaminase, the enzyme responsible for inactivating GABA (vigabatrin and valproate) or by directly stimulating GABA receptors.

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Metformin should never be prescribed for patients with renal disease or severe pulmonary or cardiac disease. Metformin is contraindicated with concurrent use of iodine containing contrast agents.

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Chemically, most drugs are either weak acids or weak bases. In an acidic environment, as in the stomach, acidic drugs are unionized according to the following simple equation: where A is an acidic drug and the excess hydrogen ions drive the equation to the left. In an alkaline environment, as in the small intestine and the majority of body fluids, basic drugs are unionized according to the following simple equation: where B is a basic drug and the deficit of hydrogen ions drives the equation to the right. Thus, acidic drugs are preferentially absorbed in the stomach and basic drugs are preferentially absorbed in the intestine. In practice however, because of the large surface area of the small intestine, the majority of drug absorption takes place there. Nevertheless, alteration of stomach pH can alter the absorption characteristics of acidic drugs.

Zovirax 500mg


Ciclosporin is an immunosuppressant normally used to prevent transplant rejection. Its mode of action in psoriasis is not completely understood, but it has anti-inflammatory actions. This highly zovirax 500mg drug is reserved for psoriasis that is resistant to other systemic treatment and it should only be used under supervision of a dermatologist. Efalizumab is a monoclonal antibody that inhibits the activation of T lymphocytes. It is licensed for severe plaque psoriasis resistant to other systemic treatment and phototherapy.


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