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A mixture of soluble (rapid and short duration of action) and isophane human insulin twice a day is the most commonly used regime. However, since the duration of action of insulin preparations varies from patient to patient, combinations of different preparations have to be determined for individual patients. The aim of insulin therapy is to achieve the best possible control of blood glucose concentration, without precipitating hypoglycaemic episodes, to avoid complications. Insulin is ineffective orally and has to be administered by injection. The usual route is subcutaneously, though the soluble rapid-acting preparations can be given intravenously in emergencies.

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PSide effects of psychostimulant relationships include insomnia, restlessness, irritability, nervousness, dizziness, night and sometimes psychosis. Dr Lot Parkinson first derived this disease in palsy.

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This is because normally calcium ions are exchanged for sodium ions across the cardiac muscle cell membrane at the end of a contraction and thereby removed from the cell. If the NaK ATPase pump is inhibited, the concentration of sodium ions in the cell increases reducing the concentration gradient for exchange with calcium ions.

Authored by Dr. Sanjay Awasthi, MD

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Like all drugs, once they have entered the systemic circulation, contrast agents have the potential to be distributed to all parts of the body, although they do not cross cell membranes easily.

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This process is known as transcription and is catalysed by an enzyme called RNA polymerase. The mRNA leaves the nucleus and attaches itself to ribosomal ribonucleic acid in the cytoplasm of the cell.

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Extensive impetigo needs treating with a systemic antibacterial such as flucloxacillin. There are many topical antibacterials available.

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