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Zopiclone is molecularly distinct from benzodiazepine pms zopiclone 7.5mg and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid GABA in the central nervous system, via modulating benzodiazepine receptors in the same way that benzodiazepine drugs do. Zopiclone is a sedative. It works by causing a depression or tranquilization of the central nervous system. After prolonged use, the body can become accustomed to the effects of zopiclone. When the dose is then reduced or the drug is abruptly stopped, withdrawal symptoms may result.

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  • Reduction in blood pressure also improves cardiac output.
  • They were originally developed from mono-iodinated pyridine derivatives (in the reduce toxicity led to tri-iodinated benzene derivatives.
  • This approach carries the risk that relapse may occur as the dose is reduced, particularly if this is done too quickly.
  • For treatment of anxiety, benzodiazepines such as diazepam and oxazepam are used because they have a slower onset of action with a longer duration than others.
  • Mood disorders are associated with changes in regional brain function, which is different to those seen in non-depressed patients who feel sad.
  • Their mode of action is complicated by the fact that currently seven serotonin receptor sub-types are recognized, further into is significance of the the brain and most is known about are inhibitory autoreceptors.
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It is used specifically to treat thyroid tumours. Radioactive iodine is also used to treat thyrotoxicosis.

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However, a major problem with MAOI drugs is that they produce a number of potentially fatal interactions with other drugs and common foods. Many foods contain tyramine, for example red wines, some pickled foods, yeast extract, particular cheeses and some vegetables, including soya and broad beans.

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Over the next few years, following the Health and Social Care Act prescribing by nurses and pharmacists was introduced.

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