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The thalamus acts as a relay station for sensory information coming into the cerebrum and plays a role in the control of sleep and wakefulness. The reticular activating system is a network of neural pathways extending from the brain stem to the thalamus and other parts of the limbic system.

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These are receptors for many hormones and neurotransmitters and are coupled to effector systems by a G-protein. The β-adrenoreceptor was the first of this type to be characterized and others seem to be similar. The structure is a single polypeptide chain spanning the membrane, folded into seven transmembrane domains and coupled to a G-protein. G-proteins are found on the inside of the membrane and act as transducers between receptors and cellular effectors. They are made up of three subunits one of which activity.


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Falciparum is resistant to chloroquine in most parts of the world.

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Calcium channel blockers are used to treat ischaemic heart disease, arrhythmia and hypertension. This is a diverse group of drugs, which fall into three classes.

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When glucose concentration falls to normal insulin secretion drops back to basal levels.

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