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The mesolimbic and mesocortical pathways are dopamine-containing neurones that run from an area in the midbrain called the ventral tegmentum to the limbic system and the prefrontal area of the cerebral cortex respectively. These are areas of the brain that are normally involved in behavioural and emotional functions.

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Sensory information coming into the cerebrum is interpreted by specific areas of the cortex. Movement of body parts is controlled by another area of the cortex.

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