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For patients who do not respond to topical therapy, systemic drugs such as methotrexate, ciclosporin, efalizumab and acitretin can be used.
29.05.2020
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These are unlicensed medicines that have not been given a Marketing Authorization by the Medicines and Healthcare Products Regulatory Agency and can only be obtained from the pharmaceutical company or manufacturer. This is a major group of anthelmintics.
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Podiatrists are specifically mentioned in the Medicines Act as being exempt from some of its provisions, which means that they can administer and supply certain POM from a specified list providing they are registered and qualified to do so. Non-medical prescribing is a relatively new means by which members of the health care professions who are not medically qualified can prescribe drugs to patients under certain conditions.
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ACE inhibitors should not be used in pregnancy. Angiotensin II receptor antagonists are used to treat cardiac failure and hypertension.
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However, cardiac glycosides have a very low therapeutic ratio and can be very toxic. Slowing of AV conduction can lead to AV block and arrhythmias.
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