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The efficacy of mebendazole in the treatment of helminthic infections varies in patients as a function of preexisting diarrhea, GI transit time, degree of infection, and helminth strain; cure rates are usually lower than average in patients who have massive infections and in patients with hypermotility of the GI tract. Although other anthelmintics e. Mebendazole is used for the treatment of ascariasis caused by Ascaris lumbricoides. Albendazole, mebendazole, or pyrantel pamoate are considered the drugs of choice for the treatment of ascariasis. Mebendazole or albendazole are considered the drugs of choice for the treatment of filariasis caused by Mansonella perstans. Mebendazole also has been used for the treatment of onchocerciasis filariasis caused by Onchocerca volvulus, but ivermectin usually is considered the drug of choice for this infection. Mebendazole is used for the treatment of intestinal hookworm infections caused by Ancylostoma duodenale or Necator americanus in single or mixed infections. Albendazole, mebendazole, or pyrantel pamoate are considered the drugs of choice for intestinal hookworm infections. Mebendazole has been used for the treatment of cutaneous larva migrans creeping eruption caused by dog and cat hookworms. However, cutaneous larva migrans usually is self-limited with spontaneous cure after several weeks or months and other drugs albendazole, ivermectin, thiabendazole usually are recommended if treatment is indicated.

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They have the same effect on central nervous tissue as they have on peripheral nervous tissue; that is, they inhibit conduction of nerve impulses. The first effects are tremor and restlessness because inhibitory pathways are affected first.

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Because podiatrists are likely to be treating fungal infections of the feet, some prescription-only antifungal drugs have been added to the list of exemptions for qualified podiatrists registered with the Health Professions Council.

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