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He wonders if these could be side effects of the colestipol and if they are what he should do. What can you tell him. Mr Jones is a widower aged few years ago.

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She is not sure why she is being asked to take methotrexate at all and she thinks it very strange that she has been told to take the drug once a week only. Discuss how you could reassure Mrs Begum about the need to take methotrexate in her case, about the once weekly dosage and about the side effects and how likely they are to affect her.

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