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Malignant hyperthermia is a severe reaction to certain drugs that are often used during invasive procedures or surgery. Medical marijuana medical cannabis is a medicine that is plant based. There are two species of medical marijuana; 1 Cannabis. Corticosteroid drugs such as prednisone and prednisolone are commonly used to treat asthma, allergic reactions, RA, and IBD. What is drug abuse?

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Common side effects include sleepiness and trouble with coordination. Diazepam was patented in by Hoffmann-La Roche. Diazepam is mainly used to treat anxiety, insomnia, panic attacks and symptoms of acute alcohol withdrawal. It is also used as a premedication for inducing sedation, anxiolysis, or amnesia before certain medical procedures e. Benzodiazepines have a relatively low toxicity in overdose.

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Because of the existence of benzodiazepine receptors, it seems likely that there must be either an endogenous benzodiazepine or an endogenous anxiolytic substance, although none has been conclusively identified yet. For treatment of anxiety, benzodiazepines such as diazepam and oxazepam are used because they have a slower onset of action with a longer duration than others.

  • These approaches are still very much in the experimental stages.
  • This was to be funded from existing prescribing budgets and, as such, should be substitute prescribing not additional, as still applies today.
  • Adverse effects of neuraminidase inhibitors are bronchospasm with zanamivir, which is inhaled, and gastrointestinal disturbances with oseltamivir.
  • Calcium channel blockers are used to treat ischaemic heart disease, arrhythmia and hypertension.

However, as one of the main functions of the liver is the metabolism of toxic substances produced during normal metabolic processes, it is not surprising that the majority of drug metabolism takes place in the liver. Some drugs are almost completely inactivated by first pass metabolism in the liver.

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If the NaK ATPase pump is inhibited, the concentration of sodium ions in the cell increases reducing the concentration gradient for exchange with calcium ions. Thus, the concentration of calcium ions within the cell rises.

Small particle size favours systemic absorption whereas large particle size discourages absorption into the systemic circulation. A drug commonly given by inhalation for a local effect is salbutamol, used to treat asthma. Many general anaesthetics are given in gaseous form clearly intended to have a systemic effect. Drugs can also be given by injection. Methods of injection include subcutaneous, intramuscular, intravenous, intra-arterial, intra-articular, intraspinal and epidural. Drugs injected subcutaneously or intramuscularly have to diffuse between loose connective tissue or muscle fibres.

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Such combinations should be avoided. Adverse effects of macrolides are nausea, vomiting, diarrhoea, deafness (with high doses but reversible) and jaundice. Chloramphenicol also binds to the Resistance to chloramphenicol occurs due to activity of bacterial enzymes. Because it is extremely toxic to bone marrow, its use is reserved for life-threatening infections where no other antibiotic is effective. Tuberculosis is caused by Mycobacterium tuberculosis and Mycobacterium bovis.


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