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They block release of noradrenaline at sympathetic nerve endings and therefore cause vasodilation and reduced peripheral vascular resistance.
Anxiety can be associated with pain and breathing difficulties. Anxiety can be a reaction to major life events, such as moving house, changing jobs or bereavement.
Most drugs are treated as potentially toxic substances and are metabolized by the liver.
Adverse reactions can occur with any drug use and can be either related to or unrelated to the expected pharmacological effect. Variation in effect of a drug can occur in different individuals and indeed in the same individuals on different occasions.
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