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Cells in a solid tumour can be in three different states: those that are dividing, possibly in continuous cell cycle; those that are resting in the G those that are no longer able to divide. Cells that are dividing are the best targets for chemotherapy, but they may only represent but cells that are resting are often resistant to cytotoxic drugs and can re-enter the cell cycle after a course of chemotherapy.
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Sensory neurons from peripheral sensory receptors feed into the RAS, which appears to filter sensory messages going to the cerebral cortex, so that some sensory information reaches conscious awareness and some does not.
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