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For the second time in six months, ezetimibe Zetia, a featherweight LDL bad cholesterol fighter, has taken a hit, and this blow could well end its career. The referee, with the initials FDA emblazoned on his white lab coat, has begun the countdown. A vigorous advertising campaign resulted in billions of dollars in sales. After five years, except for a decreased number of coronary artery bypasses in the Vytorin group, there were no differences in the incidence of strokes and heart attacks. Also analyzed in that issue of the Journal were two other similar ongoing studies in England.

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This private and confidential program provides product free of charge to eligible individuals, primarily the uninsured who, without our assistance, could not afford needed Merck medicines. A single application may provide for up to 1 year of product free of charge to eligible individuals and an individual may reapply as many times as needed. You are a US resident and have a prescription for a Merck product from a health care provider licensed in the United States. You do not have mail order zetia or other coverage for your prescription medicine. You cannot afford to pay for your medicine. If you do not meet the prescription drug coverage criteria, your income meets the program criteria, and there are special circumstances of financial and medical hardship that apply to your situation, you can request that an exception be made for you.

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Ezetimibe is used alone or in combination with other antilipemic agents i. Efficacy of ezetimibe, alone or in fixed combination with simvastatin, in patients with Fredrickson type I, III, IV, or V dyslipidemias has not been established.

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We conducted a population-based, retrospective, time-series analysis using the data collected by IMS Health in the US and Compuscript in Canada from January 1, to December 31, The main outcome measure was monthly number of prescriptions for ezetimibe-containing products. Ezetimibe remains commonly used in both the US and Canada. The diverging patterns of ezetimibe use in the US and Canada requires further investigation as it reveals that a common evidence base is eliciting very different utilization patterns in neighboring countries. However, the remaining uncertainty of ezetimibe makes it difficult to predict how its use has changed over time. Furthermore, since statins have a strong evidence-base and are the most commonly used lipid-lowering agents, we also evaluated statin use between countries to determine how ezetimibe use compares with statin use.


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