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Lipitor is a medication used to reduce lipid and cholesterol levels in certain groups of patients.
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What is atorvastatin Lipitor? Atorvastatin is used together with diet to lower blood levels of bad cholesterol low-density lipoprotein, or LDL, to increase levels of good cholesterol high-density lipoprotein, or HDL, and to lower triglycerides a type of fat in the blood. Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors. What are the possible side effects of atorvastatin Lipitor? Get emergency medical help if you have signs of an allergic reaction : hives ; difficulty breathing; swelling of your face, lips, tongue, or throat. In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure.
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Atorvastatin is indicated as an adjunct to diet for reduction of elevated total cholesterol total-C, LDL-cholesterol LDL-C, apolipoprotein B, and triglycerides in adults, adolescents and children aged 10 years or older with primary hypercholesterolaemia including familial hypercholesterolaemia heterozygous variant or combined mixed hyperlipidaemia Corresponding to Types IIa and IIb of the Fredrickson classification when response to diet and other nonpharmacological measures is inadequate. Atorvastatin is also indicated to reduce total-C and LDL-C in adults with homozygous familial hypercholesterolaemia as an adjunct to other lipid-lowering treatments e. LDL apheresis or if such treatments are unavailable. Prevention of cardiovascular events in adult patients estimated to have a high risk for a first cardiovascular event see section 5. The patient should be placed on a standard cholesterol-lowering diet before receiving Atorvastatin and should continue on this diet during treatment with Atorvastatin. The dose should be individualised according to baseline LDL-C levels, the goal of therapy, and patient response. The usual starting dose is 10 mg once a day. Adjustment of dose should be made at intervals of 4 weeks or more. The maximum dose is 80 mg once a day.
Any prescriptions from any other state cannot be filled and will be returned in the mail. Weight Loss. Baby Care. Sexual Health. Quit Smoking.
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Teva Pharmaceutical has launched the first generic Lipitor product to hit the UK market, as 's huge-selling cholesterol drug reaches its final patent expiries. Israel-based generics company Teva said it has made available generic atorvastatin film-coated tablets in 10mg, 20mg, 40mg and 80mg strengths to be used in the treatment of high cholesterol and in the prevention of cardiovascular disease. Research from Keele University had also previously predicted the low cost of atorvastatin would see doctors switch patients from alternative treatment simvastatin. The UK marks one of the final markets for Lipitor to lose exclusivity, with generics available in the US since November Whether through training, delivering solutions or devising digital strategies, we Advanced search.

Atorvastatin was patented in, and approved for medical use in the United States in The primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease . Studies suggest that high-dose statin therapy may play a plaque-stabilizing role in people with acute coronary syndrome and thrombotic stroke. Statins, including atorvastatin, have a small beneficial effect on preventing the loss of kidney function and on reducing loss of protein in urine in people with cardiovascular disease. There is tentative evidence that statins such as atorvastatin may decrease the risk of contrast-induced nephropathy CIN.
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Risk of myopathy: Increased by coadministration with fibrates, niacin, cyclosporine, macrolides, combinations of HIV protease inhibitors eg, saquinavir plus ritonavir, lopinavir plus ritonavir, tipranavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, and fosamprenavir plus ritonavir, or azole antifungals. Temporary therapy discontinuation recommended for patients with acute surgical or medical conditions, elective major surgery, or serious condition suggestive of a myopathy or risk factor predisposing to development of lipitor 40 mg generic failure secondary to rhabdomyolysis. Rare reports of immune-mediated necrotizing myopathy IMNM, characterized by increased serum creatine kinase that persists despite discontinuation of statin. SLCO1B1 polymorphism is thought to have a lesser effect on the more hydrophilic statins eg, rosuvastatin, fluvastatin compared with those that are more lipophilic eg, atorvastatin, simvastatin. Other genetic polymorphisms of elimination eg, CYP, P-glycoprotein for each individual drug must also be considered, to explain variability for statin clearance among patients that exhibit SCLO1B1 polymorphism.
In, Lipitor had the top U. Even today, after its patent loss in, atorvastatin is still one of the most prescribed medications in the U. As a drug class, statins are used by over 35 million people in the U. Statins are usually the first drug used to treat people with high cholesterol levels or heart disease. They help to reduce the risk of stroke and heart attacks, heart surgery, or chest pain angina due to coronary heart disease. If you have high cholesterol plus diabetes, high blood pressure, obesity, or a history of smoking, statins may be especially helpful for you.

Atorvastatin is used as an adjunct to nondrug therapies i. Atorvastatin in fixed combination with amlodipine is used in patients for whom treatment with both atorvastatin and a calcium-channel blocking agent buy clonidine canada. Safety and efficacy of atorvastatin for primary prevention of cardiovascular disease have been established in several randomized, double-blind, placebo-controlled studies in patients without clinical evidence of CHD. Lipoprotein concentrations were lowered to levels similar to those observed with atorvastatin 10 mg daily in previous clinical studies. Treatment with atorvastatin did not reduce the risk of death from cardiovascular or noncardiovascular causes. However, atorvastatin therapy did not reduce overall mortality.
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Lipitor 40 mg generic 4.7/5 in 104 product reviews
Time spent on developing a CMP should save time when the patient returns for review with the supplementary prescriber rather than the doctor.
27.10.2020
Antonia
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The sulphonamides were the first drugs found to be effective in the treatment of systemic infections and although they do still have some specific uses, for example treatment of toxoplasma infections in patients with HIV, they are not much used nowadays because of bacterial resistance and the development of more effective drugs, which are less toxic.
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16.10.2019
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