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Duloxetine Cymbalta 30 mg and 60 mg capsules can be prescribed on the Pharmaceutical Benefit Scheme PBS for people with a major depressive disorder.
In addition to depression, doctors can prescribe Cymbalta to treat anxiety that lasts for at least six months, pain from diabetic nerve damage, fibromyalgia, and long-term muscle or bone pain. It works by increasing the levels of the neurotransmitters serotonin and norepinephrine, which help regulate mood and may block pain signals traveling through the brain. The researchers noted that use of Cymbalta could result in fewer side effects than the drugs traditionally used for the condition, such as non-steroidal anti-inflammatory drugs, or NSAIDs, which can lead to gastrointestinal bleeding, and opioids like, which often lead to constipation. They concluded that doctors may consider adding antidepressants, such as Cymbalta to the treatment regimens for patients with osteoarthritis. The FDA requires that Cymbalta carry a black-box warning about the risk of suicide among people who use the antidepressant. Cymbalta may increase the risk for suicidal thoughts or behaviors if you are 24 years old or younger. Doctors usually do not prescribe Cymbalta for anyone younger than
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Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. In patients of all ages who are started on antidepressant therapy, monitor closely for worsening, and for emergence of suicidal thoughts and behaviors. Duloxetine hydrochloride is a white to slightly brownish white solid, which is slightly soluble in water. The 20 and 60 mg capsules also contain iron oxide yellow. Do not chew or crush. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time. For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to the medication before increasing to 60 mg once daily. Nevertheless, if a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily. The safety of doses above mg once daily has not been adequately evaluated.
Cymbalta is an antidepressant approved to treat mood and pain disorders. It works by preventing the body from reabsorbing two neurotransmitters: serotonin and norepinephrine. The drug has a long list of interactions, and possible side effects include nausea, increased sweating and withdrawal symptoms. Eli Lilly and Company manufactures the medication. The U. Food and Drug Administration first approved the antidepressant in
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Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. Duloxetine was approved for medical use in the United States in The main uses of duloxetine are in major depressive disorder, generalized anxiety disorder, neuropathic pain, chronic musculoskeletal pain, and fibromyalgia. Duloxetine is recommended as a first-line agent for the treatment of chemotherapy-induced neuropathy by the American Society of Clinical Oncology, as a first-line therapy for fibromyalgia in the presence of mood disorders by the German Interdisciplinary Association for Pain Therapy, as a Grade B recommendation for the treatment of diabetic neuropathy by the American Association for Neurology and as a level A recommendation in certain neuropathic states by the European Federation of Neurological Societies. Duloxetine was approved for the treatment of major depression in It thus did not recommend duloxetine as a first line treatment for major depressive disorder, given the then high cost of duloxetine compared to inexpensive off-patent antidepressants and lack of increased efficacy.

Duloxetine affects chemicals in the brain that may be unbalanced in people with depression. Duloxetine is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old. Duloxetine is also used to treat pain caused by nerve damage in adults with diabetes diabetic neuropathy. Do not take duloxetine within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. A dangerous drug interaction could occur.
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Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not cymbalta 30 mg drug it for a longer time than your doctor ordered. Ask your doctor if you have any questions. Swallow the delayed-release capsule whole with or without food. Do not chew, crush, or break the capsule. You will need to use this medicine for several weeks before you begin to feel better.
Duloxetine Cymbalta 30 mg and 60 mg capsules can be prescribed on the Pharmaceutical Benefit Scheme PBS for people with a major depressive disorder. J Affect Disord ;

Back to Medicines A to Z. It's used to treat depression and anxiety. It's also used to treat nerve pain, such as fibromyalgia, and can be used to treat stress aciclovir 800mg tablets incontinence in women. Duloxetine is not suitable for some people. To make sure it's safe for you, tell your doctor if you. You can take duloxetine with or without food, but it's best to take it at the same time each day.
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