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Suxamethonium is metabolized at its site of action by the enzyme pseudocholinesterase.
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At the synapse, the neurons do not touch each other but are separated by a microscopic gap, the synaptic cleft.
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Acetylcholine, noradrenaline and serotonin all play a role in inducing sleep. GABA, dopamine and some neuropeptides influence sleep-inducing activity in cholinergic neurons.
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