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They are phosphorylated in infected cells and then compete with the normal nucleotides for incorporation into viral DNA or RNA. This results in irreversible inhibition of viral polymerase. (Note: a nucleoside is a base [either purine or pyrimidine] plus a sugar molecule; a nucleotide is a base plus a phosphorylated sugar molecule. See Figure for a diagram of a nucleotide. ) Aciclovir is an analogue of guanosine nucleoside. It is used to treat herpes infections.

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Antiviral drugs are discussed in Chapter Organisms called dermatophytes cause the majority of superficial fungal infections of the skin, hair and nails. The most common dermatophytes that infect humans belong to the trichophyton, epidermophyton and microsporum families.
02.04.2018
Finn
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Any health care professional who trains to be a supplementary prescriber could prescribe prescription-only analgesics if it was appropriate to the individual clinical management plan. ( applies to members of the health care professions.
29.10.2020
Isolde
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The higher the concentration of iodine in a contrast agent the greater is the positive radiographic contrast that can be achieved. The latest non-ionic dimeric contrast agents have six iodine atoms per molecule.
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They also reduce the number of some receptors, which may contribute to the therapeutic action, but their complete mechanism of action is unknown. Examples of tricyclic antidepressants include imipramine and amitriptyline (for use of amitriptyline in neuropathic pain.
12.08.2019
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