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Nifedipine is a dihydropyridine calcium antagonist that lowers BP by peripheral vasodilatation with only mild negative inotropic and chronotropic effects. From: Comprehensive Hypertension, Ehud Grossman, Franz H. Messerli, in Comprehensive Hypertension, The advantages of nifedipine use are rapid onset of action and lack of central nervous system depression. Nifedipine is the most extensively studied agent for rapid control of BP, and until was used for acute BP lowering in hospitalized patients. After sublingual administration, the onset of action is within 1 to 5 minutes with a maximal effect at 20 to 30 minutes. The duration of action of a single dose of nifedipine is about 3 to 5 hours.
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Nifedipine was granted FDA approval on 31 December A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Nifedipine capsules are indicated to treat vasospastic angina and chronic stable angina. Nifedipine is an inhibitor of L-type voltage gated calcium channels that reduces blood pressure and increases oxygen supply to the heart. Nifedipine blocks voltage gated L-type calcium channels in vascular smooth muscle and myocardial order requip online.
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When you first start taking nifedipine you may get a order requip online or feel flushed. These symptoms usually go after a few days. A number of different brands of nifedipine are available. Not all brands have the same effect, so each time you receive a supply, check to see if it looks the same as before. If different, discuss it with your pharmacist who will advise you. Nifedipine is given to treat high blood pressure hypertension, or to help prevent angina chest pain.

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