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Common side effects include confusion and sleepiness.
The President of the United States manages the operations of the Executive branch of Government through Executive orders. The President of the United States issues other types of documents, including but not limited to; memoranda, notices, determinations, letters, messages, and orders. This prototype edition of the daily Federal Register on FederalRegister. While every effort has been made to ensure that the material on FederalRegister. Sponsors of ANDAs do not have to repeat the extensive clinical testing otherwise necessary to gain approval of a new drug application NDA. Wyeth's NDA was originally approved in
IV administration can cause severe tissue injury, including burning, gangrene, or thrombophlebitis, necessitating fasciotomy, skin graft, or amputation. Severe tissue injury can occur from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration. Respiratory fatalities reported with use in children 2 years; avoid other drugs with respiratory depressant effects. Use caution in asthma, hepatic impairment, peptic ulcer disease, respiratory impairment, bone marrow suppression, anaphylaxis in susceptible individuals. May impair core body temperature regulation; caution when taking medications with anticholinergic effects, heat exposure, or strenuous exercise. Depresses hypothalamic thermoregulatory mechanism; exposure to extreme temperatures may cause hypo- or hyperthermia. Monitor closely in patients with cardiovascular disease, hepatic impairment, Reye syndrome, or history of sleep apnea.
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Promethazine is used for treating allergic reactions and nausea and vomiting, and to sedate patients undergoing surgery or who are giving birth. Some of its characteristic side effects include dizziness and drowsiness. Because promethazine can cause serious side effects in young children and when given intravenously, its use in these situations should be avoided. Promethazine, initially developed in France in the s, was approved for use in the U. The drug is not only used in the treatment of allergic reactions, such as hay fever, but it can also be used as a sedative, to prevent motion sickness, and to treat nausea and vomiting including morning sickness. This may cause potentially irreversible damage to tissues such as the skin, including gangrene a dangerous, potentially fatal condition that involves the loss of blood flow to an area of tissue, causing it to break down and die. Instead, promethazine should be given by intramuscular injection. This risk for extravasation prompted a boxed warning the most serious drug labeling warning from the U. Food and Drug Administration in late
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It is used to treat allergic reactions and to treat or prevent nausea and vomiting from illness or motion sickness. Interactive Tools Allergies Quiz.
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Promethazine should not be used in a child younger than 2 years old. Promethazine can cause severe breathing problems or death in a child younger than 2. It works by changing the actions of chemicals in your brain. Promethazine also acts as an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body. Promethazine is used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

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It is used to ease pain. All drugs may cause side effects. It is used to ease allergy signs. Com …. If suppository is soft, chill in a refrigerator or run cold water over it. It is Minocycline For Sale used to treat sleep problems.
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Controlled Substance. Phenergan is used to treat allergic reactions.
- Phenergan Promethazine HCl Suppositories are for rectal administration only.
- To insert suppository: First remove the foil wrapper and moisten the suppository with cold water.
- It is used to treat allergic reactions and to treat or prevent nausea and vomiting from illness or motion sickness.
- Your doctor may also prescribe promethazine to relieve allergy symptoms like runny nose and watery, red eyes, or prevent and treat motion sickness.
- Each rectal suppository contains 50 mg promethazine HCl with ascorbyl palmitate and polysorbate 80 in a specially blended base of saturated vegetable fatty acids.
- When using this medication in children 2 years and older, the lowest effective dosage should be used, and other drugs that affect breathing should be avoided.
- These drugs work to treat and prevent various symptoms by blocking the effects of histamine, a chemical in the body that is responsible for symptoms of allergies and motion sickness and also plays a role in pain perception and wakefulness.
Motion sickness: 25mg 30—60mins before travel; may repeat in 8—12hrs; maintenance 25mg twice daily. Dehydrated or ill children esp.
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The use of promethazine via intraarterial administration or subcutaneous administration is contraindicated due to such risks. Proper intravenous administration is well generally tolerated; however, due to the increased risk of severe tissue necrosis and injury, the preferred route of administration is deep intramuscular injection.
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The cause of multiple sclerosis is unknown and there is no phenergan suppository 25 mg. Interferon β has been used for patients with relapsing intermittent multiple sclerosis who can walk unaided. However, this drug is no longer recommended by NICE for this purpose. Short courses of corticosteroids are used during exacerbations and seem to reduce the effect of a relapse. Spasticity is a common symptom in multiple sclerosis.

It is useful in patients who are allergic to penicillin. Adverse reactions to vancomycin are fever, rashes and rarely ear and kidney toxicity. Adverse effects of aminoglycosides are deafness, kidney damage and allergy. People with myasthenia gravis should not take them because they can impair neuromuscular transmission. Streptomycin is an aminoglycoside, which is reserved for use in treating tuberculosis (see below).
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Treatment of gout aims to control acute attacks with analgesics and colchicine and in the longer term to reduce circulating uric acid levels either by inhibiting its production with allopurinol or by encouraging its excretion by the kidneys with probenecid or sulfinpyrazone. Osteoarthritis is primarily a degenerative joint disease, but as joint destruction occurs this creates local inflammation.
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Drugs used to treat asthma and chronic bronchitis are summarized Although asthma is considered to be a reversible condition, severe acute attacks can cause obstruction that can take days to reverse and in some cases is not reversible at all.
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