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Bicalutamide has a molecular weight of

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Bicalutamide is used in combination with a gonadotropin-releasing hormone GnRH luteinizing hormone-releasing hormone analog e. If PSA concentrations increase substantially and consistently during bicalutamide therapy, the possibility of clinical progression should be evaluated. For patients with objective progression of disease and an elevated serum PSA, temporary withdrawal of bicalutamide therapy may be considered. Withdrawal of bicalutamide in such patients can be associated with a decrease in PSA. The mechanism of this response to bicalutamide withdrawal has not been determined, but may involve the development of mutations at the androgen receptor.

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What is bicalutamide, and how does it work mechanism of action? Bicalutamide is an oral medication that is used for treating cancer of the prostate. Androgens an example of which is testosterone are hormones that are produced and released by the adrenal glands. Male traits that also are influenced by androgens include facial and body hair, and small breasts. Anti-androgens prevent the action of androgens by blocking the receptors for androgens on the cells of tissues, for example, the cells of the prostate gland. Bicalutamide is thought to prevent the growth of prostate cancer by blocking the effects of androgens on the cancer cells. Bicalutamide was approved by the FDA in What are the side effects of bicalutamide? Alcohol may worsen this reaction, and so it should be cautiously consumed. LHRH analogs may increase blood glucose and worsen diabetes.

Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a composition of the R -bicalutamide and S -bicalutamide enantionmers. Bicalutamide binds to the androgen receptor. A governmentally-recognized ID casodex 50 mg generic uniquely identifies the product within its regulatory market. Bicalutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Bicalutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors but not for progestogen, estrogen, or glucocorticoid receptors.

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Antiandrogen therapy may cause morphological changes in spermatozoa; based on findings in animal reproduction studies and its mechanism of action, advise male patients with female partners of reproductive potential to use effective contraception during treatment and for days after administering final dose administered. Based on animal studies, therapy can lead to inhibition of spermatogenesis and may impair fertility in males of reproductive potential; long-term effects on male fertility not studied. Contraindicated for use in casodex 50 mg generic women because it can cause fetal harm; not indicated for use in females; there are no human data on use in pregnant women; in animal reproduction studies, oral administration of bicalutamide to pregnant rats during organogenesis caused abnormal development of reproductive organs in male fetuses at exposures approximately 0. Nonsteroidal antiandrogen, competitively binds androgen receptors and inhibits testosterone stimulation of cell growth in prostate cancer. Your list will be saved and can be edited at any time. No Results.

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In combination with luteinizing hormone-releasing hormone LHRH analogue in stage D 2 metastatic prostate carcinoma. Take at the same time each day. Start treatment at same time as starting LHRH analogue. Moderate to severe hepatic impairment. Males with female partners of reproductive potential should use effective contraception during therapy and for days after final dose. Nursing mothers.

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It is classified as an anti-androgen. For more detail, see How this drug works section below. Note: If a drug has been approved for one use, physicians may elect to use this casodex 50 mg generic drug for other problems if they believe it may be helpful. You will be checked regularly by your doctor while you are taking bicalutamide, to monitor side effects and check your response to therapy. Periodic blood work to monitor your complete blood count CBC as well as the function of other organs such as your kidneys and liver will also be ordered by your doctor.

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