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In addition, macrophages present virus to T lymphocytes, so there is direct spread from cell to cell without the virus entering plasma where it would be attacked by antibodies. HIV infection leads to AIDS when sufficient T lymphocytes have been destroyed and it is diagnosed when there is the presence of opportunistic infections. These are many and include atypical tuberculosis, herpes, chicken pox and shingles, cytomegalovirus, candida and other fungal infections and protozoan infections including pneumocystis and toxoplasma. There is no cure for HIV infection. The aim of drug therapy is to slow or stop disease progression by using a combination of different antiviral drugs.


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Their use cannot be justified for trivial illnesses but they may be used for life-threatening conditions when the benefits outweigh the risks.

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