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Consumers and health professionals are advised that the TGA is investigating the potential contamination of 'sartan' blood pressure medicines. Angiotensin receptor blockers are a class of medicines that is used to treat high blood pressure also known as hypertension. The issue was first identified in July in valsartan-containing medicines that were manufactured using an active pharmaceutical ingredient API sourced from a Chinese API manufacturer. Some products supplied in Australia used APIs from these sources. N -nitroso compounds are commonly found in low levels in a variety of foods, particularly smoked and cured meats, as well as in some drinking water and in air pollution. Long-term exposure, over years, can increase an individual's risk of developing cancer.

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  • Blocking the AT 1 receptor stops the vasoconstrictive effects of angiotensin.
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Intravenous anaesthetics are used to induce general anaesthesia, followed by an inhalation anaesthetic for maintenance, and for short surgical procedures. Propofol is commonly used for both induction and maintenance anaesthesia. Premedication is the use of drugs to reduce a patients anxiety and to prevent parasympathetic effects of the anaesthetic. Muscle relaxants and analgesics are used as adjuncts to anaesthesia, respectively to cause muscle relaxation and aid surgery and to reduce patient discomfort post-operatively. Local anaesthetics are also known as local analgesics because they cause the loss of the sensation of pain in a part of the body.


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