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Common side effects include headaches, heartburn, and flushed skin. Sildenafil acts by blocking phosphodiesterase 5 PDE 5, an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. The primary indication of sildenafil is treatment of erectile dysfunction inability to sustain a satisfactory erection to complete intercourse. Its use is now one of the standard treatments for erectile dysfunction, including for men with diabetes mellitus. Tentative evidence suggests that sildenafil may help men who experience antidepressant -induced erectile dysfunction. Sildenafil and other PDE5 inhibitors are used off-label to alleviate vasospasm and treat severe ischemia and ulcers in fingers and toes for people with secondary Raynaud's phenomenon ; these drugs have moderate efficacy for reducing the frequency and duration of vasospastic episodes.

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Viagra increases blood flow in the penis area, which helps to achieve a stable erection for men who have problems with erectile dysfunction. The action of Viagra lasts up to 4 hours, which is long enough to enjoy several full sexual acts. Do not take Viagra if you are not planning any sexual activity within several hours. However, If you plan to try Viagra for the first time, do not take more than 50 mg of the drug. For men over 65 years of age, patients with kidney, liver, or cardiovascular disease, the recommended dosage of Viagra should be reduced to 25 mg. Always consult your doctor about the exact dosage of the drug to avoid overdose and side effects.
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The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider.
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Both only work when a man is sexually aroused. Cialis lasts for around 36 hours compared with only 4 to 5 hours for Viagra.
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