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Flutamide mg First Choice 1st line treatment for all patients with tumour flare in advanced prostate cancer.

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Head-to-head studies of GnRH agonists are lacking in the field of prostate cancer. Despite the inevitable progression to castration-resistant prostate cancer CRPC in most patients receiving ADT, monitoring of testosterone levels needs to improve in routine practice and physicians should not overlook the benefits of continued ADT in their patients when introducing one of the various new treatment options for CRPC. For improved survival outcomes, there remains a need to tailor ADT treatment regimens, novel hormonal agents and chemotherapy according to the individual patient with advanced prostate cancer. Prostate cancer is the most frequently occurring cancer among European men, with an estimated incidence of, varying from 25 to per, populations in different European countries and an estimated 92, deaths in. In the USA, incidence of prostate cancer is within this European range at per, populations according to the Surveillance, Epidemiology, and End Result program. Hereditary factors are important for determining the risk of developing prostate cancer and exogenous factors may have an impact on the risk of progression. However, in general, the risk factors for prostate cancer are poorly understood and consequent advice on prevention is not possible. Therefore, the management of prostate cancer focuses on treating the disease, and the hormone dependence of prostate cancer has been recognized for decades. As a consequence, testosterone suppression has been the standard palliative treatment in men with advanced prostate cancer for many years.

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All drugs are deemed to have the same RAG status as they have for adults unless stated otherwise. Links to key documents, national programmes of care, and clinical reference groups are found below. Triptorelin is preferred gonadorelin analogue for prostate cancer. NB:Amber initiated if a course of treatment is prescribed by the GP to cover reinstatement of gonadorelin analogue therapy if doses of the latter have been missed by 3 months or more. The mg starting dose and the first 80mg maintenance dose will be administered by the specialist. Powder and solvent for suspension for injection 10mg, 20mg, 30mg Pasireotide for the treatment of Cushings Disease and acromegaly NHSE commissioned drug - see Specialised Commissioning: Key documents.

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Decapeptyl SR injection is a hormone treatment that has different uses in men, women and children. In men, Decapeptyl injections are given to treat prostate cancer.

  • All drugs are deemed to have the same RAG status as they have for adults unless stated otherwise.
  • Restrictions: Restricted to specialist initiation.
  • Commissioning responsibility of NHS England.
  • Single-centre single-blind randomised active-controlled trial.
  • There are no documented cases of toxic effects when absorbed through intact skin.
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