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PAUL W. Linezolid disrupts bacterial growth by inhibiting the initiation process of protein synthesis—a mechanism of action that is unique to this class of drugs. It is generally well tolerated, with myelosuppression being the most serious adverse effect. As a nonselective inhibitor of monoamine oxidase, caution is recommended when used with adrenergic or serotonergic agents e. Judicious use of this medication should help physicians treat patients with multidrug-resistant infections. The growing antimicrobial resistance of certain microorganisms is now a worldwide concern.
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- Linezolid is not active against infections caused by Gram-negative pathogens, and treatment should be started only after specialist microbiological advice.
- This ultimately prevents the translation and replication of bacterial proteins.
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- Linezolid LNZ is the first member of a new synthetic class of antimicrobials known as oxazolidinones with activity against many important pathogens including multidrug-resistant tubercle Bacillus, methicillin-resistant Staphylococcus and Streptococcus.
- Linezolid LNZ is the first member of a new synthetic class of antimicrobials known as oxazolidinones with activity against many important pathogens including multidrug-resistant tubercle Bacillus, methicillin-resistant Staphylococcus and Streptococcus.
- Vancomycin used to be the reference antibiotic in this indication, but new molecules have been commercialized, such as linezolid.
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Physiotherapists and radiographers may administer local anaesthetics in some circumstances under patient group directions. Certain analgesics can be accessed and supplied by podiatrists in the course of their professional practice, some of which are prescription-only medicines.
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