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Montelukast sodium is a leukotriene antagonist of growing interest as an alternative therapy for asthma across different age groups due to its bronchoprotective, anti-inflammatory and anti-allergic properties. Today, montelukast treats millions of patients around the world with market sales estimated around 5 billion US dollars per year Young, Figure 1. Redrawn from the atomic coordinates of the crystal structure of montelukast Thun et al. Asthma, a chronic inflammation manifesting as shortness of breath, wheeze and chest tightness Pawankar, ; Global Initiative for Asthma GINA, is raising concerns in public health due to the increase in the incidence of cases over the last decades. Montelukast has also anti-allergic action, thus protecting against allergen-induced asthma and preventing exercise-induced asthma Leff et al.

Singulair is indicated for prevention of exercise-induced bronchoconstriction EIB in patients 6 years of age and older. Singulair is indicated for the relief of symptoms of seasonal allergic rhinitis in patients 2 years of age and older and perennial allergic rhinitis in patients 6 months of age and older. Singulair should be taken once daily in the evening. There have been no clinical trials in patients with asthma to evaluate the relative efficacy of morning versus evening dosing. The pharmacokinetics of montelukast are similar whether dosed in the morning or evening. Efficacy has been demonstrated for asthma when montelukast was administered in the evening without regard to time of food ingestion.
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Hi Dr My 10 month old son seems to suffer with continual congestion and upper respiratory issues, his dad is an asthmatic, we have been to a pediatric pulmonologist who said that it would be hard to test at this age for the same condition, in the interim we have put him on soya milk which has helped! We also often use a course of monte air sprinkles which work really well and my son is clear and well while on them but after the 14 day course he is clear for a day or 2 and then the congestion returns. My question is whether it is advisable for my son to be on Monte Air as a continual maintenance program? Are the side affects of continued use something to avoid even though the medication works so well? Or is snottiness just something we need to ride out as being part and parcel of little ones and not stress over it, unless of course it leads to fever and to his chest like it so often does?
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ECG's were recorded while patients exercised until angina developed. You should treat it with the same urgency as a heart attack.
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However, they contain fewer radio-opaque iodine atoms and therefore are less effective as contrast agents.
19.01.2021
Bettina
Verified
Although there are probably not as many diseases of the respiratory system as there are of the cardiovascular system, there are still a number of important groups of drugs that are used to treat respiratory disorders and their use can be life saving. In order to understand diseases of the respiratory system and how they can be treated, it is necessary to have an overview of the normal function of the respiratory system; that is the structures involved, the mechanism of breathing and gas exchange and the control and variation of breathing rate.
26.05.2020
Gottlieb
Verified
It is increasingly common over the age of those commonly occurring such as lung cancer, breast cancer and colon cancer as well as much rarer conditions, some of which occur almost exclusively in children (for example retinoblastoma).
24.08.2020
Susanna
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These are of doubtful therapeutic value, yet bring relief to many patients particularly those with COPD.
30.03.2016
Florian
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