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It is thought to be the most commonly prescribed medication to combat type 2 diabetes in the world, and has been safely and effectively treating type 2 diabetes for over 60 years.
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Treatment of type 2 diabetes mellitus, particularly in overweight patients, when dietary management and exercise alone does not result in adequate glycaemic control. After 10 to 15 days the dose should be adjusted on the basis of blood glucose measurements. A slow increase of dose may improve gastrointestinal tolerability. Regular assessment of renal function is necessary see section 4. In patients at an increased risk of further progression of renal impairment and in the elderly, renal function should be assessed more frequently, e. Factors that may increase the risk of lactic acidosis see section 4.
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