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Not surprisingly, they have a similar effect to ACE inhibitors but this is brought about by preventing angiotensin II from binding to its receptors. An example is valsartan.
As this happens, the EDV also increases and it follows that there is an increase in the force of contraction to restore cardiac output.
Although the lungs are the major site of infection, the organism can also infect other tissues such as bones, joints and the brain.
They are taken orally.