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This is a condition where there is fibrosis of the skin, connective tissues and muscle causing restriction of flexion and contraction of the limbs. Internal organs including lungs, liver and heart can all be affected and the condition can prove fatal.

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Conventionally, micro-organisms include bacteria, viruses and fungi; protozoa and parasitic worms are parasites.

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This could be because excessive amounts of glutamate are released in motor neuron disease and this is toxic to neurons. Riluzole must be used under specialist supervision.

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