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It is also used to treat the signs and symptoms of benign prostatic hyperplasia BPH, such as frequent need to urinate, a sensation of not emptying the bladder completely or pain while urinating.

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In inflammatory disease their exact mode of action is unknown but they inhibit the migration of leukocytes and proliferation of lymphocytes in rheumatoid arthritis. They also reduce release of enzymes in phagocytic cells and inhibit phospholipase A prostaglandin and leukotriene synthesis. Chloroquine and hydroxychloroquine are sometimes used to treat systemic and discoid lupus erythematosus, but should not be buy tadalafil uk online for psoriatic arthritis. Because of the risk of retinopathy, long-term therapy should be reserved for cases in which all other DMARDs have failed. Immunosuppressants, such as azathioprine, ciclosporin and methotrexate, can be used to treat severe inflammatory disease. Their use depends on their ability to inhibit the activity and proliferation of lymphocytes and other leukocytes and because of this they are very toxic to the bone marrow.

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Mercaptopurine is metabolized by xanthine oxidase. It should be used with caution in combination with allopurinol because allopurinol inhibits xanthine oxidase.

  • Penicillins bind to the cell wall of bacteria and prevent cross-linking of proteoglycan chains that stabilize the cell wall.
  • Angiotensin-converting enzyme inhibitors similarly can lead to increased lithium levels and the two drugs should only be used together with caution and frequent monitoring of lithium blood levels.
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Severe acute asthma is treated as an emergency with oxygen, inhalation of salbutamol and possibly inhaled antimuscarinics and intravenous and oral corticosteroids, intravenous salbutamol, aminophylline and antibiotics if necessary. Less serious allergic rhinitis and hay fever are treated mainly with antihistamines and decongestants.

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Improvement takes about two to three weeks. Hypokinesia and rigidity are both reduced but tremor is not.

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( applies to members of the health care professions. ) General anaesthesia refers to a loss of sensation accompanied by a change or loss of consciousness.

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High doses of prilocaine can cause methaemoglobinaemia and cyanosis.

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Local anaesthetics cause varying degrees of vasodilation. The combination of a fall in heart rate and peripheral vasodilatation can result in a fall in blood pressure and fainting.

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