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  • One of the drugs, valproate, is normally prescribed for epilepsy.
  • References The Chartered Society of Physiotherapy Prescribing Rights for Physiotherapists an update, Chartered Society of Physiotherapy, London.
  • The effect of suxamethonium is not reversed by the use of anticholinesterase drugs, but would be prolonged.
  • Drugs used to treat these disorders often interact with neurotransmitters or receptors.
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Nausea and vomiting are common with most anti-cancer drugs and are caused by toxic effects on the chemotrigger zone of the central nervous system. Another adverse effect of cancer chemotherapy is known as tumour lysis syndrome. This is a collection of symptoms caused by the death of many cells in the tumour. A significant symptom is the production of large amounts of uric acid as a result of the breakdown of nucleic acids. High plasma levels of uric acid can precipitate gout, or interfere with treatment for pre-existing gout, or uric acid can deposit in the kidneys and cause kidney damage. Concurrent use of allopurinol can reduce the production of uric acid.


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In Pagets disease, osteoclasts, the cells that digest bone during the normal bone remodelling process, become hyperactive and osteoblasts, the cells that form new bone are unable to replace bone at the same rate.

09.02.2020
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