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While there is fairly widespread uptake of PGDs in diagnostic radiography, there is also a wide range of good and suboptimal practice. At a non-medical prescribing conference for radiographers, it was noted that some PGDs intended for use by radiographers were being used by administrative staff. Two examples were offered laxatives and topical anaesthetic cream. In both cases, the administrator was personally responsible for posting out these medicines to the patient, in accordance with a PGD. There is a second problem associated with this arrangement, regarding the use of the postal service as part of a PGD arrangement. Where does liability rest.

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Resistance to antimicrobial drugs can be innate or acquired. With innate resistance an entire bacterial species or a certain percentage of a population are naturally resistant to a drug. For example, Pseudomonas aeruginosa has always been resistant to flucloxacillin. Acquired resistance happens when bacteria that were once sensitive to a drug become resistant. The gene that codes for resistance is transferred from one bacterium to another.


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For example, inhibition of acetylcholinesterase leads to increased parasympathetic effects. Consequences of this are bronchospasm, a fall in heart rate and hypotension.

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